Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50105679'
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50105679((E)-N-Hydroxy-3-[4-(4-nitro-benzenesulfonylamino)-...)
Affinity DataIC50:  700nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50105679((E)-N-Hydroxy-3-[4-(4-nitro-benzenesulfonylamino)-...)
Affinity DataIC50:  900nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50105679((E)-N-Hydroxy-3-[4-(4-nitro-benzenesulfonylamino)-...)
Affinity DataEC50:  2.00E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed