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Found 4 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50248431'
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | N-hydroxy-3-(2-phenethyl-1-propyl-1...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | N-hydroxy-3-(2-phenethyl-1-propyl-1...)
Affinity DataIC50:  227nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | N-hydroxy-3-(2-phenethyl-1-propyl-1...)
Affinity DataIC50:  227nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | N-hydroxy-3-(2-phenethyl-1-propyl-1...)
Affinity DataIC50:  227nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent