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Found 5 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 11' and Ligand = 'BDBM50273526'
TargetHistone deacetylase 11(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50:  3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50:  15nMAssay Description:Inhibition of NanoLuc-tagged HDAC11 (unknown origin) by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50: <500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50: <500nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50: <500nMAssay Description:Activity was measured using electrophoretic mobility shift assays with full length human recombinant HDAC proteins and fluorescently labeled peptide ...More data for this Ligand-Target Pair
In DepthDetails US Patent