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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM50020872'
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020872(CHEMBL3287010 | US9216962, CFH426-S)
Affinity DataIC50:  106nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020872(CHEMBL3287010 | US9216962, CFH426-S)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed