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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT1' and Ligand = 'BDBM50010380'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone-lysine N-methyltransferase EHMT1


(Homo sapiens (Human))
BDBM50010380
PNG
(CHEMBL3263626)
Show SMILES NC(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)CC1CCCCC1
Show InChI InChI=1S/C18H28N6O3/c19-11(6-10-4-2-1-3-5-10)7-12-14(25)15(26)18(27-12)24-9-23-13-16(20)21-8-22-17(13)24/h8-12,14-15,18,25-26H,1-7,19H2,(H2,20,21,22)/t11?,12-,14-,15-,18-/m1/s1
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PC sid
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Patents


Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of methyltransferase activity of EHMT1 (unknown origin)-mediated dimethylation of a biotinylated histone H3 peptide at lysine-9 by FRET-ba...


ACS Med Chem Lett 5: 293-7 (2014)


Article DOI: 10.1021/ml4002503
BindingDB Entry DOI: 10.7270/Q2N58NWS
More data for this
Ligand-Target Pair