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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Homo sapiens lysine demethylase 2A (KDM2A)' and Ligand = 'BDBM276047'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
Show InChI InChI=1S/C20H20N6O/c1-2-27-20-6-4-3-5-15(20)8-10-26-13-19(22-14-26)17-11-16(7-9-21-17)18-12-23-25-24-18/h3-7,9,11-14H,2,8,10H2,1H3,(H,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10174003 (2019)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
Show InChI InChI=1S/C20H20N6O/c1-2-27-20-6-4-3-5-15(20)8-10-26-13-19(22-14-26)17-11-16(7-9-21-17)18-12-23-25-24-18/h3-7,9,11-14H,2,8,10H2,1H3,(H,23,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair