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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Homo sapiens lysine demethylase 2A (KDM2A)' and Ligand = 'BDBM276059'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
Show InChI InChI=1S/C17H12Cl2N6/c18-13-3-1-2-12(17(13)19)8-25-9-16(21-10-25)14-6-11(4-5-20-14)15-7-22-24-23-15/h1-7,9-10H,8H2,(H,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10174003 (2019)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
Show InChI InChI=1S/C17H12Cl2N6/c18-13-3-1-2-12(17(13)19)8-25-9-16(21-10-25)14-6-11(4-5-20-14)15-7-22-24-23-15/h1-7,9-10H,8H2,(H,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair