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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Homo sapiens lysine demethylase 2A (KDM2A)' and Ligand = 'BDBM276060'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2A (KDM2A)


(Homo sapiens (Human))
BDBM276060
PNG
(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
Show InChI InChI=1S/C18H12ClF3N6/c19-17-12(2-1-3-13(17)18(20,21)22)8-28-9-16(24-10-28)14-6-11(4-5-23-14)15-7-25-27-26-15/h1-7,9-10H,8H2,(H,25,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair