BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor (HIF-PH2)' and Ligand = 'BDBM123039'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor (HIF-PH2)


(Rattus norvegicus (Rat))
BDBM123039
PNG
(US8742138, 24)
Show SMILES OC(=O)CNC(=O)c1c2c(cccc2c(O)oc1=O)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C18H11Cl2NO6/c19-11-5-4-8(6-12(11)20)9-2-1-3-10-14(9)15(18(26)27-17(10)25)16(24)21-7-13(22)23/h1-6,25H,7H2,(H,21,24)(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 30n/an/an/an/an/an/a



Betta Pharmaceuticals Co., Ltd.

US Patent


Assay Description
HIF-PHD2 activity was measured using homogeneous TR-FRET technology (see also, US2008/004817; Dao J H et al., Anal Biochem. 2009, 384:213-23). To eac...


US Patent US8742138 (2014)

More data for this
Ligand-Target Pair