Found 3 Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50393283' TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 4.17E+3nMAssay Description:Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubat...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 2.55E+3nMAssay Description:Activation of human HIF1alpha expressed in human U2OS cells assessed as increase in VEGF expression by RT-PCR analysisMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 2.06E+3nMAssay Description:Activation of GFP-tagged HIF1alpha expressed in human U2OS cells assessed as HIF1alpha nuclear translocation by high content imaging assayMore data for this Ligand-Target Pair
