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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340558'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340558
PNG
(4′-(2-tert-Butylphenoxy)-3′-(3-p-tolyl...)
Show SMILES Cc1ccc(NC(=O)Nc2cc(ccc2Oc2ccccc2C(C)(C)C)-c2ccccc2C(O)=O)cc1
Show InChI InChI=1S/C31H30N2O4/c1-20-13-16-22(17-14-20)32-30(36)33-26-19-21(23-9-5-6-10-24(23)29(34)35)15-18-28(26)37-27-12-8-7-11-25(27)31(2,3)4/h5-19H,1-4H3,(H,34,35)(H2,32,33,36)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 560n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair