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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340781'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340781
PNG
((E)-1-(5-(But-2-en-1-yl)-4-propoxy-2′-(1H-te...)
Show SMILES CCCOc1c(C\C=C\C)cc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H30N6O2/c1-4-6-9-20-17-21(23-10-7-8-11-24(23)27-31-33-34-32-27)18-25(26(20)36-16-5-2)30-28(35)29-22-14-12-19(3)13-15-22/h4,6-8,10-15,17-18H,5,9,16H2,1-3H3,(H2,29,30,35)(H,31,32,33,34)/b6-4+
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair