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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340788'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340788
PNG
(4'-(2-tert-butylphenoxy)- 3'-(3-(2-chlorophenyl) u...)
Show SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2ccccc2C(C)(C)C)c(NC(=O)Nc2ccccc2Cl)c1
Show InChI InChI=1S/C31H29ClN2O5/c1-31(2,3)22-9-5-8-12-27(22)39-28-16-14-20(19-13-15-26(38-4)21(17-19)29(35)36)18-25(28)34-30(37)33-24-11-7-6-10-23(24)32/h5-18H,1-4H3,(H,35,36)(H2,33,34,37)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 620n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair