BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340838'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340838
PNG
(US9765018, Example 298)
Show SMILES CCCOc1c(NC(=O)Nc2ccc(C)cc2)cc(cc1C(CC)c1ccccc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C33H34N6O2/c1-4-19-41-31-29(26(5-2)23-11-7-6-8-12-23)20-24(27-13-9-10-14-28(27)32-36-38-39-37-32)21-30(31)35-33(40)34-25-17-15-22(3)16-18-25/h6-18,20-21,26H,4-5,19H2,1-3H3,(H2,34,35,40)(H,36,37,38,39)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair