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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340839'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340839
PNG
(US9765018, Example 313)
Show SMILES CCCC(Oc1ccc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1-c1nnn[nH]1)c1ccccc1Cl
Show InChI InChI=1S/C31H29ClN6O2/c1-3-8-28(25-11-6-7-12-26(25)32)40-29-18-15-21(23-9-4-5-10-24(23)30-35-37-38-36-30)19-27(29)34-31(39)33-22-16-13-20(2)14-17-22/h4-7,9-19,28H,3,8H2,1-2H3,(H2,33,34,39)(H,35,36,37,38)
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PC cid
PC sid
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US Patent
n/an/a 610n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair