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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340840'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340840
PNG
(US9765018, Example 316)
Show SMILES FC(F)(F)CCOc1c(CC2CC2)cc(cc1NC(=O)Nc1ccc(cc1)C1CC1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H29F3N6O2/c31-30(32,33)13-14-41-27-22(15-18-5-6-18)16-21(24-3-1-2-4-25(24)28-36-38-39-37-28)17-26(27)35-29(40)34-23-11-9-20(10-12-23)19-7-8-19/h1-4,9-12,16-19H,5-8,13-15H2,(H2,34,35,40)(H,36,37,38,39)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 40n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair