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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM340841'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM340841
PNG
(US9765018, Example 319)
Show SMILES FC(F)(F)CCOc1c(CC2CC2)cc(cc1NC(=O)Nc1ccc(OC(F)(F)F)cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H24F6N6O3/c29-27(30,31)11-12-42-24-18(13-16-5-6-16)14-17(21-3-1-2-4-22(21)25-37-39-40-38-25)15-23(24)36-26(41)35-19-7-9-20(10-8-19)43-28(32,33)34/h1-4,7-10,14-16H,5-6,11-13H2,(H2,35,36,41)(H,37,38,39,40)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 90n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair