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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM50234044'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM50234044
PNG
(CHEMBL4102416 | US9765018, Example 145)
Show SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2cccc3CCCc23)c(NC(=O)Nc2ccc(C)cc2)c1
Show InChI InChI=1S/C31H28N2O5/c1-19-9-13-23(14-10-19)32-31(36)33-26-18-22(21-11-15-27(37-2)25(17-21)30(34)35)12-16-29(26)38-28-8-4-6-20-5-3-7-24(20)28/h4,6,8-18H,3,5,7H2,1-2H3,(H,34,35)(H2,32,33,36)
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Patents


Similars

US Patent
n/an/a 1.59E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair