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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase' and Ligand = 'BDBM50234046'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM50234046
PNG
(CHEMBL4067223 | US9765018, Example 151)
Show SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2cccc3CCCCc23)c(NC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C31H28N2O5/c1-37-27-16-14-21(18-25(27)30(34)35)22-15-17-29(38-28-13-7-9-20-8-5-6-12-24(20)28)26(19-22)33-31(36)32-23-10-3-2-4-11-23/h2-4,7,9-11,13-19H,5-6,8,12H2,1H3,(H,34,35)(H2,32,33,36)
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PC cid
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Similars

US Patent
n/an/a 1.12E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company; Syngene International Limited; Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9765018 (2017)

More data for this
Ligand-Target Pair