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Found 2 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50234038'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50234038(CHEMBL4097275)
Affinity DataIC50:  87nMAssay Description:Inhibition of IDO1 (unknown origin) using tryptophan as substrate preincubated for 15 mins followed by substrate addition by high-throughput screenin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50234038(CHEMBL4097275)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production preincubated with cells followed by IFN-g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed