Found 14 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50300305'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataKi: 3.40E+4nMAssay Description:Competitive inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in mouse B16 cells assessed as kynurenine formation by spectrophotometryMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of N-terminal his-tagged human indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as N'-formylkynurenine formation by spec...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli using D-Trp as substrateMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in mouse B16 cells assessed as kynurenine formation by adjusted cell-based spectrophotometryMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute of Technology
Curated by ChEMBL
Indian Institute of Technology
Curated by ChEMBL
Affinity DataEC50: 59nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair