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Found 5 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50303910'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed