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Found 5 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50391358'
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50:  20nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50:  620nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50:  620nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50:  1.20E+3nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed