Found 5 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50391358'
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair