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Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase' and Ligand = 'BDBM50100961'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-5'-monophosphate dehydrogenase


(Bacillus anthracis)
BDBM50100961
PNG
(CHEMBL3329563)
Show SMILES CN1CCN(CC1)C(=O)c1cc(NC(=O)NC(C)(C)c2cccc(c2)C(\C)=N\O)ccc1Cl
Show InChI InChI=1S/C24H30ClN5O3/c1-16(28-33)17-6-5-7-18(14-17)24(2,3)27-23(32)26-19-8-9-21(25)20(15-19)22(31)30-12-10-29(4)11-13-30/h5-9,14-15,33H,10-13H2,1-4H3,(H2,26,27,32)/b28-16+
PDB

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometry


ACS Med Chem Lett 5: 846-50 (2014)


Article DOI: 10.1021/ml500203p
BindingDB Entry DOI: 10.7270/Q23J3FN3
More data for this
Ligand-Target Pair