Found 4 Enz. Inhib. hit(s) with Target = 'Inositol 1,4,5-trisphosphate receptor type 1' and Ligand = 'BDBM50323706' TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at rat recombinant IP3R1 expressed in chicken DT40 cells assessed as calcium release from intracellular storesMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKd: 0.140nMAssay Description:Displacement of [3H]IP3 from rat recombinant IP3R1 binding core residue (224-604) expressed in chicken DT40 cells by equilibrium competitive binding ...More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKd: 0.420nMAssay Description:Displacement of [3H]IP3 from rat recombinant N-terminal IP3R1 (1-604) expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Cambridge
Curated by ChEMBL
University Of Cambridge
Curated by ChEMBL
Affinity DataKd: 0.900nMAssay Description:Displacement of [3H]IP3 from full-length rat recombinant IP3R1 expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
