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Found 6 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50091737'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataIC50:  0.810nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of integrin alphaIIb-beta3 in platelet aggregation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataKd:  2.40nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-...)
Affinity DataKd:  0.160nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed