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Found 2 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50143851'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143851(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50:  16nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143851(5-[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1...)
Affinity DataIC50:  118nMAssay Description:Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed