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Found 3 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM374375'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374375(US10246456, Example 528 | US10577367, Example 528)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374375(US10246456, Example 528 | US10577367, Example 528)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374375(US10246456, Example 528 | US10577367, Example 528)
Affinity DataEC50: <1.00E+3nMAssay Description:The cell-based assays is based on IL-6 ELISA quantification. Briefly, A549 cells are cultured in DMEM with 10% FBS medium. When cells reach 80% confl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent