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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interleukin-10 (IL-10)' and Ligand = 'BDBM192717'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-10 (IL-10)


(Homo sapiens (Human))
BDBM192717
PNG
(HG-9-91-01 derivative, 6)
Show SMILES CCOc1cc(ccc1Nc1ncc2CN(C(=O)N(c3ccc(OC)cn3)c2n1)c1c(C)cccc1Cl)C1CCN(C)CC1
Show InChI InChI=1S/C33H36ClN7O3/c1-5-44-28-17-23(22-13-15-39(3)16-14-22)9-11-27(28)37-32-36-18-24-20-40(30-21(2)7-6-8-26(30)34)33(42)41(31(24)38-32)29-12-10-25(43-4)19-35-29/h6-12,17-19,22H,5,13-16,20H2,1-4H3,(H,36,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Broad Institute



Assay Description
Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...


ACS Chem Biol 11: 2105-11 (2016)

More data for this
Ligand-Target Pair