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Found
1
Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM387288'
Target
Interleukin-2
(Homo sapiens (Human))
Lupin
US Patent
Ligand
BDBM387288
(N-(3′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
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Affinity Data
IC50: 550nM
Assay Description:
Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...
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Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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