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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM387297'
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387297(US10292981, Example 121)
Affinity DataIC50:  150nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-2(Homo sapiens (Human))
Lupin

Curated by ChEMBL
LigandPNGBDBM387297(US10292981, Example 121)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent