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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein 1' and Ligand = 'BDBM335736'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 1


(Homo sapiens (Human))
BDBM335736
PNG
(6-{[1-(2-Phenyl-thiazol-4-ylmethyl)-1H-pyrrolo[3,2...)
Show SMILES Nc1nccc2cc(CNc3nccc4n(Cc5csc(n5)-c5ccccc5)ccc34)ccc12
Show InChI InChI=1S/C27H22N6S/c28-25-22-7-6-18(14-20(22)8-11-29-25)15-31-26-23-10-13-33(24(23)9-12-30-26)16-21-17-34-27(32-21)19-4-2-1-3-5-19/h1-14,17H,15-16H2,(H2,28,29)(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.34E+3n/an/an/an/an/an/a



Kalvista Pharmaceuticals Limited

US Patent


Assay Description
KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...


US Patent US9738641 (2017)

More data for this
Ligand-Target Pair