Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM50322299'
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  930nMAssay Description:Antagonist activity at human GPR54 receptor assessed as inhibition of metastin-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed