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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273024'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273024
PNG
((R)-2-(7-oxo-5-phenyl-6,7-dihydro[1,3]thiazolo[5,4...)
Show SMILES O=C(Oc1ccccc1)N1CCC[C@@H]1c1nc2c(nc([nH]c2=O)-c2ccccc2)s1
Show InChI InChI=1S/C22H18N4O3S/c27-19-17-21(25-18(24-19)14-8-3-1-4-9-14)30-20(23-17)16-12-7-13-26(16)22(28)29-15-10-5-2-6-11-15/h1-6,8-11,16H,7,12-13H2,(H,24,25,27)/t16-/m1/s1
PDB
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PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair