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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273032'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273032
PNG
(2-[(R)-1-(phenylacetyl)pyrrolidin-2-yl]-5-[1-(trif...)
Show SMILES FC(F)(F)C1(CC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Cc1ccccc1
Show InChI InChI=1S/C21H19F3N4O2S/c22-21(23,24)20(8-9-20)19-26-16(30)15-18(27-19)31-17(25-15)13-7-4-10-28(13)14(29)11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2,(H,26,27,30)/t13-/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair