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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273035'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273035
PNG
((R)-2-[7-oxo-5-(2,2,2-trifluoroethoxy)-6,7-dihydro...)
Show SMILES FC(F)(F)COc1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C18H15F3N4O4S/c19-18(20,21)9-28-16-23-13(26)12-15(24-16)30-14(22-12)11-7-4-8-25(11)17(27)29-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,23,24,26)/t11-/m1/s1
PDB
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PC cid
PC sid
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US Patent
n/an/a 65n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair