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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273038'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273038
PNG
((R)-2-[6-(2,4-dimethoxybenzyl)-5-ethyl-7-oxo-6,7-d...)
Show SMILES CCc1nc2sc(nc2c(=O)n1Cc1ccc(OC)cc1OC)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C27H28N4O5S/c1-4-22-28-25-23(26(32)31(22)16-17-12-13-19(34-2)15-21(17)35-3)29-24(37-25)20-11-8-14-30(20)27(33)36-18-9-6-5-7-10-18/h5-7,9-10,12-13,15,20H,4,8,11,14,16H2,1-3H3/t20-/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 270n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair