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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273040'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273040
PNG
((R)-2-[5-(3-methyloxetan-3-yl)-7-oxo-6,7-dihydro[1...)
Show SMILES CC1(COC1)c1nc2sc(nc2c(=O)[nH]1)[C@H]1CCCN1C(=O)Oc1ccccc1
Show InChI InChI=1S/C20H20N4O4S/c1-20(10-27-11-20)18-22-15(25)14-17(23-18)29-16(21-14)13-8-5-9-24(13)19(26)28-12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3,(H,22,23,25)/t13-/m1/s1
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PC cid
PC sid
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US Patent
n/an/a 14n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair