BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273049'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273049
PNG
((R)-2-[5-oxo-7-(propan-2-yl)-5H-[1,3,4]thiadiazolo...)
Show SMILES CC(C)c1cc(=O)n2nc(sc2n1)[C@H]1CCCN1C(=O)Oc1ccc(F)cc1
Show InChI InChI=1S/C19H19FN4O3S/c1-11(2)14-10-16(25)24-18(21-14)28-17(22-24)15-4-3-9-23(15)19(26)27-13-7-5-12(20)6-8-13/h5-8,10-11,15H,3-4,9H2,1-2H3/t15-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 77n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair