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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273151'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273151
PNG
((R)-N-benzyl-1-[5-(2,6-difluorophenyl)-7-oxo-6,7-d...)
Show SMILES Fc1cccc(F)c1-c1nc2sc(nc2c(=O)[nH]1)N1CCC[C@@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H19F2N5O2S/c24-14-8-4-9-15(25)17(14)19-28-21(32)18-22(29-19)33-23(27-18)30-11-5-10-16(30)20(31)26-12-13-6-2-1-3-7-13/h1-4,6-9,16H,5,10-12H2,(H,26,31)(H,28,29,32)/t16-/m1/s1
PDB
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PC cid
PC sid
UniChem
US Patent
n/an/a 9n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair