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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273167'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273167
PNG
((R)-N-benzyl-1-[7-chloro-6-(2-fluorophenyl)-4-oxo-...)
Show SMILES Fc1ccccc1-c1[nH]c(=O)c2nc(sc2c1Cl)N1CCC[C@@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C24H20ClFN4O2S/c25-18-19(15-9-4-5-10-16(15)26)28-23(32)20-21(18)33-24(29-20)30-12-6-11-17(30)22(31)27-13-14-7-2-1-3-8-14/h1-5,7-10,17H,6,11-13H2,(H,27,31)(H,28,32)/t17-/m1/s1
PDB
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PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair