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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kynurenine aminotransferase II (KAT II)' and Ligand = 'BDBM107742'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM107742
PNG
(US8933095, 26)
Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1C(F)(F)F
Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-4-2-3-5-10(8)15(16,17)18)9-7-11(19)14(23)22(24)13(9)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Similars

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US Patent
n/an/a 40.7n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...


US Patent US8933095 (2015)

More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM107742
PNG
(US8933095, 26)
Show SMILES Cn1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1C(F)(F)F
Show InChI InChI=1S/C15H15F3N4O2/c1-21-12(6-8-4-2-3-5-10(8)15(16,17)18)9-7-11(19)14(23)22(24)13(9)20-21/h2-5,11,24H,6-7,19H2,1H3/t11-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 40.7n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...


US Patent US8598200 (2013)

More data for this
Ligand-Target Pair