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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'LTB4R' and Ligand = 'BDBM50317627'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(Homo sapiens (Human))
BDBM50317627
PNG
(4-(2-(2-carboxyethyl)-3-(6-(5-(2,3-dihydrobenzo[b]...)
Show SMILES OC(=O)CCCOc1cccc(CCCCCCOc2cc(cc(c2)-c2ccc3OCCOc3c2)-c2ccc(F)cc2)c1CCC(O)=O
Show InChI InChI=1S/C39H41FO8/c40-32-14-11-27(12-15-32)30-23-31(29-13-17-36-37(26-29)48-22-21-47-36)25-33(24-30)45-19-4-2-1-3-7-28-8-5-9-35(34(28)16-18-39(43)44)46-20-6-10-38(41)42/h5,8-9,11-15,17,23-26H,1-4,6-7,10,16,18-22H2,(H,41,42)(H,43,44)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 60.2n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins


J Med Chem 53: 3502-16 (2010)


Article DOI: 10.1021/jm1001919
BindingDB Entry DOI: 10.7270/Q2KW5G67
More data for this
Ligand-Target Pair