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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lactate dehydrogenase A (LDHA)' and Ligand = 'BDBM50052304'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM50052304
PNG
(CHEMBL3318529)
Show SMILES Cc1cc(C)nc(SC2=C(O)CC(CC2=O)c2ccccc2)n1
Show InChI InChI=1S/C18H18N2O2S/c1-11-8-12(2)20-18(19-11)23-17-15(21)9-14(10-16(17)22)13-6-4-3-5-7-13/h3-8,14,21H,9-10H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assay


Bioorg Med Chem Lett 24: 3764-71 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.076
BindingDB Entry DOI: 10.7270/Q2445P46
More data for this
Ligand-Target Pair