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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lactate dehydrogenase A (LDHA)' and Ligand = 'BDBM50089945'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM50089945
PNG
(CHEMBL3581183)
Show SMILES OC1=C(Sc2ccccc2Cl)C(=O)CC(C1)c1c(Cl)ccc(c1Cl)-c1cccnc1
Show InChI InChI=1S/C23H16Cl3NO2S/c24-16-5-1-2-6-20(16)30-23-18(28)10-14(11-19(23)29)21-17(25)8-7-15(22(21)26)13-4-3-9-27-12-13/h1-9,12,14,28H,10-11H2
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 108n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human LDH-A by biochemical assay


Bioorg Med Chem Lett 25: 75-82 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.008
BindingDB Entry DOI: 10.7270/Q2BR8TXC
More data for this
Ligand-Target Pair