Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Leucyl-cystinyl aminopeptidase' and Ligand = 'BDBM271311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM271311 (US10059720, Example 126) Show SMILES CCSC[C@H](N)[C@](O)(Cc1cc(OC2CCC3(CC3)CC2)ccn1)C(O)=O Show InChI InChI=1S/C20H30N2O4S/c1-2-27-13-17(21)20(25,18(23)24)12-14-11-16(5-10-22-14)26-15-3-6-19(7-4-15)8-9-19/h5,10-11,15,17,25H,2-4,6-9,12-13,21H2,1H3,(H,23,24)/t17-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...				US Patent US10059720 (2018)
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM271311 (US10059720, Example 126) Show SMILES CCSC[C@H](N)[C@](O)(Cc1cc(OC2CCC3(CC3)CC2)ccn1)C(O)=O Show InChI InChI=1S/C20H30N2O4S/c1-2-27-13-17(21)20(25,18(23)24)12-14-11-16(5-10-22-14)26-15-3-6-19(7-4-15)8-9-19/h5,10-11,15,17,25H,2-4,6-9,12-13,21H2,1H3,(H,23,24)/t17-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...				US Patent US10059720 (2018)
					More data for this Ligand-Target Pair