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Found 1 hit Enz. Inhib. hit(s) with Target = 'Leukotriene A4 hydrolase' and Ligand = 'BDBM50397956'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene A4 hydrolase


(Homo sapiens (Human))
BDBM50397956
PNG
(CHEMBL2179974)
Show SMILES N=C1CCc2ccccc2C(Cc2ccccc2)C1=O
Show InChI InChI=1S/C18H17NO/c19-17-11-10-14-8-4-5-9-15(14)16(18(17)20)12-13-6-2-1-3-7-13/h1-9,16,19H,10-12H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
3.80E+5n/an/an/an/an/an/an/an/a



Universit£ de Haute Alsace

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant LTA4H using alanine-p-nitroanilide as substrate by Dixon-plot analysis


Bioorg Med Chem 20: 4942-53 (2012)


Article DOI: 10.1016/j.bmc.2012.06.041
BindingDB Entry DOI: 10.7270/Q2RB75Q1
More data for this
Ligand-Target Pair