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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C (JMJD2C)' and Ligand = 'BDBM340052'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C (JMJD2C)


(Homo sapiens (Human))
BDBM340052
PNG
(2-{2-Methyl-7-[methyl(phenyl)amino]-2H-indazol-3-y...)
Show SMILES CN(c1ccccc1)c1cccc2c(-c3cc4nccc(C(O)=O)c4[nH]3)n(C)nc12
Show InChI InChI=1S/C23H19N5O2/c1-27(14-7-4-3-5-8-14)19-10-6-9-15-21(19)26-28(2)22(15)18-13-17-20(25-18)16(23(29)30)11-12-24-17/h3-13,25H,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9758517 (2017)


Article DOI: 10.1021/jm0303857
More data for this
Ligand-Target Pair