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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C (JMJD2C)' and Ligand = 'BDBM340053'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C (JMJD2C)


(Homo sapiens (Human))
BDBM340053
PNG
(2-(1-Methyl-1H-indazol-3-yl)-1H-pyrrolo[3,2-b]pyri...)
Show SMILES Cn1nc(-c2cc3nccc(C(O)=O)c3[nH]2)c2ccccc12
Show InChI InChI=1S/C16H12N4O2/c1-20-13-5-3-2-4-9(13)15(19-20)12-8-11-14(18-12)10(16(21)22)6-7-17-11/h2-8,18H,1H3,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 550n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9758517 (2017)


Article DOI: 10.1021/jm0303857
More data for this
Ligand-Target Pair