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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C (JMJD2C)' and Ligand = 'BDBM340058'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C (JMJD2C)


(Homo sapiens (Human))
BDBM340058
PNG
(2-[6-Chloro-1-(cyclopropylmethyl)-1H-indazol-3-yl]...)
Show SMILES OC(=O)c1ccnc2cc([nH]c12)-c1nn(CC2CC2)c2cc(Cl)ccc12
Show InChI InChI=1S/C19H15ClN4O2/c20-11-3-4-12-16(7-11)24(9-10-1-2-10)23-18(12)15-8-14-17(22-15)13(19(25)26)5-6-21-14/h3-8,10,22H,1-2,9H2,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9758517 (2017)


Article DOI: 10.1021/jm0303857
BindingDB Entry DOI: 10.7270/Q2RB76QF
More data for this
Ligand-Target Pair